11/27/2023 0 Comments Elixir vimrKalivoda KA, Steenbergen SM, Vimr ER, Plumbridge J. The first committed step in the biosynthesis of sialic acid by Escherichia coli K1 does not involve a phosphorylated N-acetylmannosamine intermediate. Microbiology and Molecular Biology Reviews : Mmbr. Diversity of microbial sialic acid metabolism. Vimr ER, Kalivoda KA, Deszo EL, Steenbergen SM. Sialic Acid metabolism and systemic pasteurellosis. Steenbergen SM, Lichtensteiger CA, Caughlan R, Garfinkle J, Fuller TE, Vimr ER. Proceedings of the National Academy of Sciences of the United States of America. Escherichia coli K1 polysialic acid O-acetyltransferase gene, neuO, and the mechanism of capsule form variation involving a mobile contingency locus. PMID 16677296 DOI: 10.1111/J.ĭeszo EL, Steenbergen SM, Freedberg DI, Vimr ER. Mobile contingency locus controlling Escherichia coli K1 polysialic acid capsule acetylation. Separate pathways for O acetylation of polymeric and monomeric sialic acids and identification of sialyl O-acetyl esterase in Escherichia coli K1. Steenbergen SM, Lee YC, Vann WF, Vionnet J, Wright LF, Vimr ER. Going for baroque at the Escherichia coli K1 cell surface. Escherichia coli K1-specific bacteriophage CUS-3 distribution and function in phase-variable capsular polysialic acid O acetylation Journal of Bacteriology. King MR, Vimr RP, Steenbergen SM, Spanjaard L, Plunkett G, Blattner FR, Vimr ER. Biosynthesis of the Escherichia coli K1 group 2 polysialic acid capsule occurs within a protected cytoplasmic compartment. Early molecular-recognition events in the synthesis and export of group 2 capsular polysaccharides. YjhS (NanS) is required for Escherichia coli to grow on 9-O-acetylated N-acetylneuraminic acid. A tale of tails: Sialidase is key to success in a model of phage therapy against K1-capsulated Escherichia coli Virology. Methods in Molecular Biology (Clifton, N.J.). Chromatographic analysis of the Escherichia coli polysialic acid capsule. Unified theory of bacterial sialometabolism: how and why bacteria metabolize host sialic acids. Control of the Escherichia coli sialoregulon by transcriptional repressor NanR. Unexpected diversity of Escherichia coli sialate O-acetyl esterase NanS. Right now those kinds of machines are mostly servers, but that level of concurrency will eventually make it’s way into desktop computing.Rangel A, Steenbergen SM, Vimr ER. While Elixir will never likely be the fastest on 1 or two cores, once you’ve solved your problem in Elixir it becomes much easier to throw 24 or (128) cores at it and see reasonable speed ups. if your basic problem is “embarrassingly parallel” and I/O limited ) What would scream “Elixir Desktop App” to me is a problem that using the increasing number of cores available on high end desktops would help. What might make more sense is to drive an Elixir app via a GUI wrapper if your underlying problem maps well to what the BEAM does well. There will likely be places where this battle is worthwhile, but I think for most applications the time to delivery penalty will be too great until more of the spadework in library interfaces is available. However, I think for Native UI Desktop Apps, Elixir is going to be an uphill battle. One way around this is to use the browser and javascript as your GUI interface.Ĭreating a Port interface to OpenGL is also pretty intriguing. There is the wx interface, but the problem with putting any GUI library in as a NIF is that it can crash the BEAM. IMHO, the BEAM would be a pretty awesome GUI app environment, but it doesn’t have a robust interface to the client windowing API. There’s a kind of chicken and egg problem here. The Little Elixir & OTP Guidebook states in the intro that Elixir that Elixir & GUI don’t mix, but several presentations at the Elixir Conf, including the Toyota Way seems to indicate that large companies have embraced Elixir for business apps. I write mostly GUI business apps, and also need a lot of reporting.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |